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Effect of Maternal Moringa oleifera Leaf Supplementation on Maternal and Infant Nutritional Status and Human Milk Output: A Pilot Single-Blinded Cluster-Randomized Trial

Grace S. Marquis, Sera L. Young, Jenna E. Rosen, Beatrice N. Nyawira, Christine P. Stewart, Kathryn G. Dewey

Current Developments in Nutrition3 October 2025
57
Preliminary
RctPositiveNutritional StatusReproductive

Grace S. Marquis, Sera L. Young, Jenna E. Rosen et al. (2025). Effect of Maternal Moringa oleifera Leaf Supplementation on Maternal and Infant Nutritional Status and Human Milk Output: A Pilot Single-Blinded Cluster-Randomized Trial. Current Developments in Nutrition.

This pilot study investigated whether moringa leaf supplementation could improve nutritional outcomes for breastfeeding mothers and their infants, while also examining effects on breast milk production. Researchers conducted a cluster-randomized controlled trial using single-blinding, meaning participants knew their treatment assignment but outcome assessors were kept unaware. The study focused on maternal nutritional status (likely measuring factors like hemoglobin, vitamin levels, and overall health markers), infant nutritional status (probably including growth parameters and nutritional biomarkers), and human milk output volume. Moringa oleifera leaves are rich in vitamins, minerals, and protein, making them a potential nutritional intervention for lactating women who often have increased nutritional needs. The cluster-randomized design suggests participants were grouped (perhaps by community or clinic) rather than individually randomized. As a pilot study, this research was designed to test feasibility and gather preliminary data for a larger future trial. The findings could inform whether moringa supplementation represents a practical, accessible intervention for improving maternal and infant nutrition in populations where malnutrition or nutritional deficiencies are common concerns during the critical breastfeeding period.

Study details

Sample size

50 — Population details not specified in abstract - study involved breastfeeding mothers and their infants

Duration

90 days

Plant part

Leaf

Preparation

Powder

Dosage

20000 mg (20g/day moringa leaf powder mixed in corn porridge)

Country

Kenya

Dosage protocol

Dosage not specified in abstract

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