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Moringa oleifera on hyperglycemia and hypertension in metabolic diseases: Systematic review, exploratory meta-analysis and meta-regression.

Mokgalaboni K, Ahmed SR, Phoswa WN, Mashaba GR, Mokgalabone TT, Ndhlala AR, Mpai S, Lebelo SL

Metabolism open12 March 2026
54
Preliminary
Meta AnalysisPositiveBlood SugarBlood Pressure

Mokgalaboni K, Ahmed SR, Phoswa WN et al. (2026). Moringa oleifera on hyperglycemia and hypertension in metabolic diseases: Systematic review, exploratory meta-analysis and meta-regression.. Metabolism open.

This systematic review and meta-analysis examined whether Moringa oleifera supplements can help manage blood sugar and blood pressure in people with metabolic disorders like diabetes and hypertension. The researchers searched multiple scientific databases and identified 20 clinical studies that tested moringa in patients with these conditions. They then combined the results statistically to get a clearer picture of moringa's effects. The analysis found that moringa supplementation was associated with modest improvements in several key health markers. For blood sugar control, moringa was linked to reductions in fasting blood glucose levels and glycated hemoglobin (a measure of long-term blood sugar control that decreased by 0.62%). For blood pressure, the results showed reductions in both systolic blood pressure (the top number, reduced by 7.50 mmHg) and diastolic blood pressure (the bottom number, reduced by 6.82 mmHg). The researchers also discovered that the effectiveness varied depending on the specific condition being treated and the geographic location where studies were conducted. This suggests that moringa's benefits may not be uniform across all populations or metabolic disorders. While these findings indicate potential benefits, the researchers emphasized that the evidence should be considered preliminary due to variations between studies and limitations in study quality.

Study details

Population

Twenty clinical studies conducted in patients with various metabolic diseases, with meta-regression indicating that specific patient conditions and geographic location (continent) significantly influenced outcomes

Dosage protocol

Specific dosage protocols not reported in abstract

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