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Metabolic adaptation to the aqueous leaf extract of Moringa oleifera Lam.-supplemented diet is related to the modulation of gut microbiota in mice

Xiaoyu Gao, Qiuhong Xie, Ling Liu, Ping Kong, Jun Sheng, Hongyu Xiang

Applied Microbiology and Biotechnology5 April 2017
View paper PubMed DOI: 10.1007/s00253-017-8233-5
16
Exploratory
Animal In VivoNeutralGut Health

Xiaoyu Gao, Qiuhong Xie, Ling Liu et al. (2017). Metabolic adaptation to the aqueous leaf extract of Moringa oleifera Lam.-supplemented diet is related to the modulation of gut microbiota in mice. Applied Microbiology and Biotechnology. doi:10.1007/s00253-017-8233-5

Researchers investigated how moringa leaf extract affects metabolism and gut bacteria in laboratory mice. The study examined whether dietary supplementation with aqueous moringa leaf extract could influence metabolic processes through changes in the gut microbiome. Gut microbiota refers to the trillions of bacteria living in the digestive system that play important roles in metabolism, immune function, and overall health. The research focused on understanding the connection between moringa consumption and bacterial populations in the intestines, and how these microbial changes might relate to metabolic adaptations in the animals. This type of research is important because the gut microbiome has emerged as a key factor in metabolic health, influencing everything from blood sugar control to fat metabolism. Understanding how moringa affects these bacterial communities could help explain some of the metabolic benefits attributed to this plant. The findings contribute to growing scientific knowledge about how dietary interventions with moringa might work at the microbial level to influence metabolism, though this was conducted in mice rather than humans.

Study details

Population

Laboratory mice (specific strain, number, and characteristics not specified in abstract)

Plant part

Leaf

Preparation

Extract Aqueous

Dosage protocol

dosage not specified in abstract

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