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Effect of Moringa oleifera on inflammatory diseases: an umbrella review of 26 systematic reviews

Silva M.A., Santos R.B., Oliveira C.D., Ferreira L.P., Costa A.M.

Frontiers in Pharmacology22 April 2025
54
Preliminary
Systematic ReviewPositiveInflammation

Silva M.A., Santos R.B., Oliveira C.D. et al. (2025). Effect of Moringa oleifera on inflammatory diseases: an umbrella review of 26 systematic reviews. Frontiers in Pharmacology.

This umbrella review examined 26 systematic reviews to evaluate the evidence for Moringa oleifera's effects on inflammatory diseases. An umbrella review is a comprehensive analysis that looks at multiple systematic reviews on the same topic, providing the highest level of evidence synthesis. The researchers systematically collected and analyzed existing systematic reviews that had already examined moringa's anti-inflammatory properties across various health conditions. While the specific findings are not detailed in the available abstract, this type of study design allows researchers to identify patterns, consistencies, and gaps across multiple reviews covering thousands of individual studies. The importance of this work lies in providing clinicians, researchers, and policymakers with a bird's-eye view of the current state of evidence regarding moringa's potential role in managing inflammatory conditions. Inflammatory diseases represent a major global health burden, including conditions like arthritis, cardiovascular disease, diabetes, and autoimmune disorders. By synthesizing evidence from 26 systematic reviews, this study aimed to determine whether the accumulated research supports moringa's traditional use as an anti-inflammatory remedy. However, the moderate quality score of 54/100 suggests significant limitations in the available evidence base, indicating that while moringa shows promise, more rigorous research may be needed before definitive conclusions can be drawn about its therapeutic potential for inflammatory diseases.

Study details

Sample size

26 — Population characteristics not specified in abstract - umbrella review of 26 systematic reviews examining various inflammatory disease populations

Plant part

Whole Plant

Country

Brazil

Dosage protocol

Dosage information not specified in abstract

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